What is Assisted Reproductive Technology (ART)?​

Assisted reproductive technology (ART) involves the direct manipulation of eggs, sperm, and embryos for infertility treatment. Assisted reproductive technologies carried out by Little Monster include in vitro fertilization (IVF) and embryo transfer (IVF-ET), intracytoplasmic sperm injection (ICSI) and assisted embryo hatching (AH). Newer assisted reproductive technologies include powerful chromosomal and genetic assessment techniques such as embryo biopsy and preimplantation genetic diagnosis (PGD). Note that artificial insemination is not an assisted reproductive technique, although it is the main means of infertility treatment. 

The following explanations will help you better understand the various assisted reproductive technologies:​

In vitro fertilization (IVF)

What is IVF?

“In vitro” is a Latin phrase that means “in glass”. In vitro fertilization (IVF) provides a controlled environment that greatly improves the chances of fertilization of the egg cell (or egg). In vitro fertilization combines the egg with the sperm in a laboratory dish containing a culture medium that provides nutrients for the fertilization and development of the egg. The fertilization process is monitored under a microscope for three days, during which the successfully fertilized egg develops into an embryo. Our team of embryologists then carefully checks the quality of the embryos to decide which embryos to select for embryo transfer, cryopreservation, or further culture and development.

History of IVF

More than 30 years ago, the world first learned about IVF. The first “IVF” Louise Brown was conceived by IVF in London in 1978.

In vitro fertilization and surgical treatment of tubal infertility

Little Monster has made significant advances in the surgical treatment of IVF and infertility. Deciding which treatment to use (IVF or surgery) depends on several factors, including maternal age, expected pregnancy rate, surgical risks, and recovery time. Accurate diagnosis of tubal infertility Understanding the type of tubal problem and the extent of tubal damage is essential to determine the best course of treatment. Little Monster uses the latest diagnostic techniques such as HSG (Hysterosalpingography) to evaluate tubal infertility. Therefore, an accurate diagnosis is a crucial first step. The easiest way to do this is to call Little Monster. We will help you schedule a personal consultation with a Little Monster allied fertility specialist. Once the diagnosis is confirmed, your fertility team will develop a comprehensive, personalized treatment plan based on the diagnosis. 

IVF process
Induction of ovulation
In vitro fertilization (IVF) requires the female partner to undergo a series of injections of potent fertility drugs to induce ovulation. These fertility drugs, such as clomiphene citrate (Clomid®), cause her ovaries to produce several mature eggs (oocytes) at the same time, rather than just one during a normal, untreated menstrual cycle. This allows women to increase their chances of conception and to be able to select the most viable embryos through an assisted reproductive technique called PGD (Preimplantation Genetic Diagnosis) that we carry out in our IVF laboratory.
 
Egg retrieval and fertilization
Egg retrieval is performed by removing oocytes from the ovaries using an intravaginal aspiration process that takes only a few minutes under light sedation. A semen sample is obtained from the male partner, and the egg and sperm are combined in an IVF laboratory. Within three to six days, the embryos that have developed from this process are evaluated and a few are selected for embryo transfer (ET).
 
3-D/4-D超声引导胚胎移植(ET):观看我们实时植入您的胚胎!
Under ultrasound guidance with 3-D/4-D real-time technology (the most precise way to transfer embryos), the embryo is instilled into the uterus through a thin, flexible plastic tube that gently passes through the opening of the cervix and leads to the inside of the uterus. You can really see the embryo transfer into your uterus! About 12 days later, a pregnancy blood test is done to determine whether the transplant led to pregnancy. 

What is ICSI? 

Intracytoplasmic sperm injection (ICSI) is a powerful assisted reproductive technique (ART) used by the Little Monster for many cases of male infertility. Intracytoplasmic sperm microinjection (ICSI) is the second major advancement in modern fertility treatment, the first being in vitro fertilization, as it enables fertility specialists to directly address infertility caused by male factors. The intracytoplasmic sperm microinjection process introduces a single sperm cell directly into each egg obtained during in vitro fertilization. The resulting embryo is then transferred into the uterus to begin pregnancy. Intracytoplasmic sperm microinjection has proven to be a truly revolutionary technique that has given new hope to many couples who are unable to conceive.

 Is ICSI right for me?

The answer depends on your diagnosis! In order to determine if intracytoplasmic sperm microinjection (ICSI) is an appropriate treatment, you need to make an accurate diagnosis. It may seem obvious, but many couples who suffer from infertility think they know what the problem is but never get the right diagnosis.

Why Use the ICSI Program? 

Intracytoplasmic sperm injection can be used for most types of male infertility, including Low sperm count No sperm in the ejaculate Impaired sperm motility (motility) Abnormal sperm morphology (the shape of the sperm) Intracytoplasmic sperm microinjection can also be helpful in rare cases of male infertility, such as Problems with sperm binding and penetrating the egg Anti-sperm antibodies (immune or protective proteins that attach to and destroy sperm) Previous or multiple failed fertilization using standard IVF culture and fertilization methods frozen sperm collected prior to cancer treatment, The quantity and quality of its sperm may be limited due to blockage leading to azoospermia. In this case, sperm can be extracted from the epididymis by microaspiration of sperm from the epididymis (MESA) or testicular sperm aspiration (TESA). 

FAQ

1If there are no embryos, can I also start the process?

 

Yes, you can! If you haven't selected a test tube center yet, we will recommend and arrange it for you. We partner with the best test tube centers in the United States, and you can make embryos in the clinics we partner with.

2How can I find a surrogate mother? Where are your surrogate mothers from?

You made the right choice! In addition to our physician-managed model, we are known for always having pre-screened surrogate mothers who can be matched right away! At Physician Care Fertility, we receive applications from women in 39 states across the United States. They must go through our meticulous pre-screening process, which includes medical, psychological, and social background screenings. We handle the details and provide the candidate who is closest to your clinic's criteria, your criteria, and your mother's personal preferences.
In this way, we are able to pair you with the ideal surrogate mother, whether she is a first-time candidate or a candidate with previous experience.

3How much is the mother's compensation fee?

 

There is no one-size-fits-all answer to this question, as the cost of maternity compensation depends on several factors. Your case manager will outline the services required during surrogacy and our compensation structure for a fixed fee. Immediately after your free consultation, we will provide a price quote. The quote will go according to your situation and preferences. At Physician Care Surrogacy, we are proud to offer transparent services and prices. Book your free consultation now to get a transparent quote to help you understand the total cost of surrogacy.

4How much does surrogacy cost?

Due to differences in the cost of compensation for surrogacy and other state-specific factors, surrogacy costs in the United States range from $120,000 to $160,000.

5How can I find a surrogate mother?

The best way to find a surrogate mother is through a reputable surrogacy agency, such as Physician's Surrogacy. Having surrogacy professionals arrange the entire process is crucial to ensure your pregnancy is safe and smooth.
Some people will turn to family members for help, while others choose to go through the surrogacy journey independently, but in both cases there is no guarantee to protect either yourself or your surrogate mother. In addition, surrogacy agencies can ensure that you have legal support throughout the process, from the surrogacy contract to the determination of parental authority. This support is essential to safeguard your rights.

6What is a surrogate mother? | Expectant parents | Doctor Care Surrogacy Center

A surrogate mother is a woman who uses embryos to carry out a pregnancy through the process of in vitro fertilization (IVF). A surrogate mother can use the mother-to-be's egg and the father-to-be's sperm to achieve a pregnancy. Surrogate mothers also offer the option of using donor eggs or sperm. There is no genetic relationship between the surrogate mother and the fetus.

7What is surrogacy?

In surrogacy, (a surrogate mother) conceives and gives birth to a baby for another woman, couple, or individual (the intended parent). The surrogate mother is not biologically related to the baby because the surrogate mother's own eggs are not used in the process. Instead, embryos are created by using sperm from the intended father or donor sperm, as well as eggs from the intended mother or donor eggs.

8Who needs a surrogate mother?

 

"Having a surrogate mother can be a viable option in the following circumstances:
Unable to conceive due to an irregular uterus
* Multiple IVF failures with no clear reason
Delaying parenthood due to career or other life circumstances.
Due to certain circumstances, it is impossible to conceive and have children of its own.
Have an underlying medical condition that could pose a significant risk to you or your baby during pregnancy
"Same-sex male couples or single fathers"

9Who is the surrogate mother?

A surrogate is a woman who surrogates and gives birth to someone else/couple who is unable to conceive or have a child naturally. In traditional surrogacy, the surrogate mother receives artificial insemination from the father's sperm/donor's sperm. The traditional surrogate mother is the biological mother of the child because her eggs are used to create the embryo. This practice is outdated and replaced by IVF surrogacy where the surrogate mother only takes on the task of pregnancy and does not provide the egg.
A surrogate mother is simply someone who conceives and delivers a child and is not genetically related to the newborn, as the mother-to-be's eggs/donor eggs are used to create the embryo. 

10Why is the cost of a surrogate mother different?

The total cost of a surrogacy arrangement includes a lot of factors such as agency fees, compensation for surrogate mothers, medical expenses, fertility clinic fees, and legal fees. However, there are many more factors that also affect surrogacy costs such as country, state, special medical conditions, etc. Therefore, the total cost incurred by surrogacy varies greatly based on these variables. It is recommended that you consult a surrogacy specialist to better understand the impact of different factors on surrogacy costs.