
In vitro experts in the United States: Is it possible to accelerate the onset of menopause in women with ovulation induction?
2024年10月24日
IVF in the United States: Are Chimeric Embryos Suitable for Transfer?
2024年10月24日The birth of a new life is the development of sperm and eggs, and being able to provide sperm and eggs is the basis for a successful pregnancy. There are many causes of infertility, among which azoospermia has caused great distress to many men. As a great fertility technology, IVF brings a glimmer of hope to patients with azoospermia and helps them realize their dreams of having children. What does azoospermia mean?
Azoospermia refers to the absence of sperm during semen examination, which means that no sperm can be found in the ejaculated semen for three consecutive times. As one of the difficult to treat infertility, azoospermia has brought profound pain to patients and countless troubles to doctors. Azoospermia accounts for about 15% -20% of male infertility patients, with various causes that can be summarized into two main categories. One is the dysfunction of the testicles themselves, known as primary azoospermia or non obstructive azoospermia. The second is that the testicular spermatogenic function is normal, but due to obstruction of the vas deferens, sperm cannot be expelled from the body, which is called obstructive azoospermia.
Reasons for male infertility:
1. Obstruction of the vas deferens
Many male friends suffer from azoospermia mainly due to blockages in their vas deferens. However, these blockages can be congenital, caused by surgical injuries in the later stages, or due to inflammation in the male body. Therefore, in order to treat azoospermia, it is necessary to first unblock the vas deferens.
2. Testicular self spermatogenic dysfunction
Dysfunction of the testicles in producing sperm can also prevent the body from producing sperm. The main causes of testicular spermatogenic dysfunction are orchitis, cryptorchidism, and azoospermia. Therefore, test tube experts suggest that men should pay attention to the causes of the disease in their daily lives, try not to keep their testicles in a high-temperature environment for a long time, prevent them from being hit by external forces, and minimize the use of cottonseed oil to reduce the risk of disease.
3. Varicocele
Varicocele is also an important cause of male azoospermia. Suffering from varicocele can affect the blood supply to the testicles, thereby affecting the sperm production function of the testicles.
4. Radiation and heat
Different people have different sensitivities to radiation and thermal radiation. Some male germinal epithelium are more sensitive to radiation, and short-term and low-dose irradiation can affect their spermatogenic function. There are also men who receive long-term thermal radiation, which significantly increases the risk of azoospermia.
In vitro fertilization in the United States helps infertile people
For people with azoospermia, as long as it is not primary azoospermia, IVF technology in the United States can help them have their own children:
1. Testicular puncture for sperm extraction
Men with azoospermia may not be able to naturally ejaculate sperm, but due to normal spermatogenesis, their testicles can still produce sperm, so testicular puncture can be used to achieve their desire for fertility. The professional anesthesiologists at Little Monster in the United States first perform local anesthesia based on the male’s physical condition. Then, under the monitoring of ultrasound, in vitro fertilization experts will search for sperm in the male testicles, epididymis, or seminiferous tubules. Afterwards, a very thin needle will be used to extract the semen. The process of sperm extraction will not cause any pain or harm to the male body, making it very safe.
2. Perecell sperm washing technology
After extracting semen, the Little Monster Reproductive Center in the United States will use advanced Perecell gradient centrifugation technology to wash and optimize the sperm. Experts dilute the obtained semen with washing solution and then centrifuge it at a high speed of 1000-2000 revolutions per minute for 10 minutes. Under the action of centrifugal force, there will be different sedimentation, forming different gradient liquid zones. So, those components that are not conducive to fertilization (such as seminal plasma, dead sperm, sperm antibodies, inflammatory cells, bacteria, mycoplasma, etc.)