
What tests do I need before traveling to the U.S. for IVF?
2024年10月24日
What is a false pregnancy? American IVF technology makes pregnancy easy!
2024年10月24日The success rate of IVF is influenced by many factors, including individual factors and technical factors, and therefore, many people may face difficulties in the process of IVF. Although women need to spend more time throughout the tube cycle, men also need to be prepared, because the high rate of sperm fragmentation is one of the main causes of infertility in many men. Next, little Monster test tube experts will discuss how to deal with the high rate of sperm fragmentation to improve the success rate of IVF.
Symptoms of a high sperm fragmentation rate:
High rates of sperm fragmentation usually refer to a high rate of sperm DNA fragmentation, which is associated with sperm DNA damage resulting from multiple causes. If the rate of sperm DNA fragmentation is high, the sperm integrity is poor, which can lead to decreased male fertility. The higher the rate of sperm DNA fragmentation, the more likely it is to lead to infertility, repeated abortions and fetal malformations.
Under normal circumstances, sperm DNA should be double-stranded and intact, but sperm DNA may break due to aging or physical and chemical factors in the environment, resulting in debris, and thus no longer intact. If the sperm DNA fragmentation rate exceeds 25%, it indicates the presence of a certain disease state. Various factors may lead to an increased rate of sperm DNA fragmentation, such as reproductive tract infection, increased testicular temperature, varicocele, chemoradiotherapy, heavy smoking, industrial pollution of the surrounding environment and heavy metals. If the rate of sperm DNA fragmentation is found to increase, it should be treated according to the reason, and develop healthy lifestyle habits, increase the intake of protein and vitamins, and adhere to exercise to reduce the rate of sperm DNA fragmentation. Men with high rates of sperm fragmentation usually develop the following symptoms:
- Infertility:
Men with a high rate of sperm fragmentation often face infertility problems, because too much fragmented sperm can affect the sperm motility and fertilization ability, reducing the chance of conception.
- Weak:
With more sperm fragmentation, the sperm energy reserves also decline, leaving the sperm unable to remain alive, thus affecting the ability to fertilize.
- Morphological abnormalities:
Men with a high rate of sperm fragmentation usually have a large number of morphologically abnormal sperm that, even with successful fertilization, may lead to problems such as abnormal embryo development or abortion.
For men with a high rate of sperm fragmentation, the US little Monster Reproductive Center offers the following strategies:
- Sperm washing to obtain high-quality sperm
In the process of sperm, men can get semen by masturbation or testicular puncture technology, test tube experts will get semen Perecoll gradient centrifugation and sperm washing, the semen mixed with detergent, then rotate in high-speed centrifuge for 10 minutes, which contains pathogens, dead sperm, inflammatory cells, bacteria and mycoplasma impurities floating on the surface, and healthy sperm will form a loose precipitation. In this way, harmful impurities and healthy sperm can be effectively separated from each other.
- Single sperm injection to improve the fertilization rate
When screening sperm, the little Monster Reproductive Center used high-power electron microscopy to observe the sperm morphology in order to clearly distinguish whether the sperm